ANTIFUNGAL STUDY OF UNCARIA GAMBIR ROXB. (UGR) EXTRACT AGAINST GANODERMA SP. IN VITRO

STUDI ANTIFUNGI EKSTRAK UNCARIA GAMBIR ROXB. (UGR) TERHADAP GANODERMA SP. SECARA IN VITRO

Authors

  • Rylo Nugroho Politeknik Negeri Pontianak Author
  • Dodi Iskandar Politeknik Negeri Pontianak Author
  • Rista Delyani Politeknik Negeri Pontianak Author
  • Danie Indra Yama Politeknik Negeri Pontianak Author
  • Muliani Politeknik Negeri Pontianak Author

DOI:

https://doi.org/10.71275/roce.v2i1.52

Keywords:

Antifungal, Bioinformatics, Ganoderma sp, Uncaria gambir Roxb, In Vitro

Abstract

Ganoderma sp. is a pathogenic fungus that causes basal stem rot in oil palms, leading to significant yield losses. This study explores the antifungal potential of Uncaria gambir Roxb. extract against Ganoderma sp. using in silico and in vitro methods. In silico analysis from the KNApSAcK and PASS Online databases identified 18 secondary metabolites with probability activity (Pa) values ranging from 0.5 to 0.7, indicating high potential. Cinchonain Ia, an alkaloid with the highest Pa value of 0.638, has poor solubility. In vitro tests on U. gambir extract at various concentrations (0%, 1.5%, 2%, 2.5%, and 3%) showed that the extract was ineffective in inhibiting the growth of Ganoderma sp. Further research with variations in solvents, extraction methods, and formulations is needed to optimize the antifungal activity of this extract.

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Author Biographies

  • Rylo Nugroho, Politeknik Negeri Pontianak

    Program Studi Budidaya Tanaman Perkebunan, Teknologi Pertanian, Politeknik Negeri Pontianak

  • Dodi Iskandar, Politeknik Negeri Pontianak

    program Studi Pengolahan Hasil Perkebunan Terpadu, Teknologi Pertanian, Politeknik Negeri Pontianak

  • Rista Delyani, Politeknik Negeri Pontianak

    Program Studi Budidaya Tanaman Perkebunan, Teknologi Pertanian, Politeknik Negeri Pontianak

  • Danie Indra Yama, Politeknik Negeri Pontianak

    Program Studi Budidaya Tanaman Perkebunan, Teknologi Pertanian, Politeknik Negeri Pontianak

  • Muliani, Politeknik Negeri Pontianak

    Program Studi Budidaya Tanaman Perkebunan, Teknologi Pertanian, Politeknik Negeri Pontianak

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Published

2025-01-20

How to Cite

ANTIFUNGAL STUDY OF UNCARIA GAMBIR ROXB. (UGR) EXTRACT AGAINST GANODERMA SP. IN VITRO: STUDI ANTIFUNGI EKSTRAK UNCARIA GAMBIR ROXB. (UGR) TERHADAP GANODERMA SP. SECARA IN VITRO. (2025). ROCE : Jurnal Pertanian Terapan, 2(1). https://doi.org/10.71275/roce.v2i1.52

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