ANTIOXIDANT OF n-HEXANE EXTRACT OF Uncaria gambir RoxbFROM PONTIANAK
ANTIOKSIDAN EKSTRAK n-HEXANE Uncaria Gambir Roxb DARIPONTIANAK
DOI:
https://doi.org/10.71275/roce.v2i2.128Keywords:
Uncaria gambir Roxb, n-hexane, antioxidant, phytochemicalsAbstract
The n-hexane extract of dried UGR leaves was obtained with a yield of 8.0 grams (16%). Phytochemical
screening revealed the presence of secondary metabolites, including phenolics, steroids, and terpenes.
The antioxidant activity was evaluated using the DPPH assay, yielding an IC50 value of 53.654 ppm,
which classified the extract as strong, falling within the 50–100 ppm range. However, n-hexane extracts
generally exhibit weaker antioxidant activity due to the nonpolar nature of the solvent, which limits the
extraction of polar antioxidant compounds such as polyphenols and flavonoids. Consequently, n-hexane extracts contain higher amounts of lipids, terpenes, and other nonpolar compounds, which are less effective at scavenging DPPH radicals compared to polar extracts like ethanol or methanol.
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