ANTIFUNGAL STUDY AGAINST CURVULARIA SP. FROM UNCARIAGAMBIR ROXB LEAF EXTRACT
STUDI ANTIFUNGAL TERHADAP CURVULARIA SP. DARI EKSTRAKDAUN UNCARIA GAMBIR ROXB
DOI:
https://doi.org/10.71275/roce.v2i1.79Keywords:
Uncaria gambir Roxb, Curvularia sp, AntifungalAbstract
Isomitrafoline and Speciophylline show the strongest general Anesthetic (92.2) compared to other ligands. This study aims to determine the effect of gambir leaf extract on the growth of Curvularia sp. fungus and the concentration of extract that can inhibit 50% of the growth of fungal colonies. The research method used was a Completely Randomized Design (CRD) with 4 variations of extract concentration (0%, 5%, 10%, and 15%), each repeated 6 times. The results showed that the highest concentration of gambir leaf extract in inhibiting fungal growth was at a concentration of 15%. LC 50% analysis revealed that the concentration required to achieve 50% inhibition was 118.16%, indicating that the effectiveness of the extract against Curvularia sp. fungus is low or less toxic
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References
Faleye, O. S., Boya, B. R., Lee, J.-H., Choi, I., & Lee, J. (2024). Halogenated Antimicrobial Agents to Combat Drug-Resistant Pathogens. Pharmacological Reviews, 76(1), 90–141. https://doi.org/10.1124/pharmrev.123.000863
Faruq, M. O., Rahim, A., Arifuzzaman, M., & Ghosh, G. P. (2024). Phytochemicals screening, nutritional assessment and antioxidant activities of A. viridis L. and A. spinosus L. leaves: A comparative study. Journal of Agriculture and Food Research, 18, 101341.
https://doi.org/https://doi.org/10.1016/j.jafr.2024.101341
Kaswi, N., Wahyuni, S., Annisa, R., Al Adawiah, P. R., & A. Salim, I. P. (2024). The Manufacture Method of Potato Dextrose Agar (PDA) as Growth Media for Airborne Mold in the Science Laboratory of SMAS Pesantren IMMIM Makassar. Lontara Abdimas : Jurnal Pengabdian Kepada Masyarakat, 5(1), 53–59.
https://doi.org/10.53861/lomas.v5i1.472
Luo, Q., Luo, L., Zhao, J., Wang, Y., & Luo, H. (2024). Biological potential and mechanisms of Tea’s bioactive compounds: An Updated review. Journal of Advanced Research, 65, 345– 363. https://doi.org/https://doi.org/10.1016/j.jare.2023.12.004
Mishra, P., Singh, U., Pandey, C. M., Mishra, P., & Pandey, G. (2019). Application of student’s t-test, analysis of variance, and covariance. Annals of Cardiac Anaesthesia, 22(4), 407– 411. https://doi.org/10.4103/aca.ACA_94_19
Pramanik, F., Satari, M. H., & Azhari, A. (2023). Cytotoxic Activity of Gambier Leave (Uncaria gambir) Ethyl Acetate Extract on Mouse Embryonic Fibroblast Cell (NIH-3T3) using MTT Assay. The Open Dentistry Journal, 17. https://doi.org/https://doi.org/10.2174/18742106-v17-e230109-2022-78
Santra, H. K., Dutta, R., & Banerjee, D. (2024). Antifungal activity of bio-active cell-free culture extracts and volatile organic compounds (VOCs) synthesised by endophytic fungal isolates of Garden Nasturtium. Scientific Reports, 14(1), 11228. https://doi.org/10.1038/s41598-024-60948-0
Singh, K., Ghosh, I., Jayaprakash, V., & Jayapalan, S. (2024). Building a ML-based QSAR model for predicting the bioactivity of therapeutically active drug class with imidazole scaffold. European Journal of Medicinal Chemistry Reports, 11, 100148. https://doi.org/https://doi.org/10.1016/j.ejmcr.2024.100148
Terrones-Fernandez, I., Rodero-De-Lamo, L., López, A., Peiró, S., Asensio, D., Castilla, R.,
Gamez-Montero, P. J., & Piqué, N. (2024). Microwave Oven Application for the Preparation and Sterilization of Microbiological Culture Media: A Feasible Method with An Adapted Water Bath and Perforable Cap. In Applied Sciences (Vol. 14, Issue 6). https://doi.org/10.3390/app14062340
Uddin, M. R., Akhter, F., Abedin, M. J., Shaikh, M. A. A., Al Mansur, M. A., Saydur Rahman, M., Molla Jamal, A. H. M. S. I., Akbor, M. A., Hossain, M. H., Sharmin, S., Idris, A. M., & Khandaker, M. U. (2024). Comprehensive analysis of phytochemical profiling, cytotoxic and antioxidant potentials, and identification of bioactive constituents in methanoic extracts of Sonneratia apetala fruit. Heliyon, 10(13), e33507. https://doi.org/https://doi.org/10.1016/j.heliyon.2024.e33507
Wyckhuys, K. A. G., Gu, B., Ben Fekih, I., Finger, R., Kenis, M., Lu, Y., Subramanian, S., Tang, F. H. M., Weber, D. C., Zhang, W., & Hadi, B. A. R. (2024). Restoring functional integrity of the global production ecosystem through biological control. Journal of Environmental Management, 370, 122446.
https://doi.org/https://doi.org/10.1016/j.jenvman.2024.122446
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